Drug Information for VUSIONTM (0.25% miconazole nitrate, 15% zinc oxide, and 81.35% white petrolatum) OintmentRx only. FOR TOPICAL USE ONLY. NOT FOR OPTHALMIC, ORAL, OR INTRAVAGINAL USE. (Barrier Therapeutics, Inc.): DESCRIPTION

  • VUSION Ointment contains the synthetic antifungal agent, miconazole nitrate (0.25%), zinc oxide (15%) and white petrolatum (81.35%) for topical use.

    The chemical name of miconazole nitrate is 1-[2, 4-dichloro-ß-{(2,4-dichlorobenzyl) oxy} phenethyl] imidazole mononitrate with empirical formula C18H14Cl4N2O•HNO3 and molucular weight of 479.15. The structural formula of miconazole nitrate is as follows:

    The zinc oxide has an empirical formula of ZnO and a molecular weight of 81.39.

    The white petrolatum, which is obtained from petroleum and is wholly or nearly decolorized, is a purified mixture of semisolid saturated hydrocarbons having the general chemical formula CnH2n+2. The hydrocarbons consist mainly of branched and unbranched chains. White petrolatum contains butylated hydroxytoluene (BHT) as stabilizer.

    Each gram of VUSION Ointment contains 2.5 mg of miconazole nitrate USP, 150 mg of zinc oxide USP, 813.5 mg of white petrolatum USP containing butylated hydroxytoluene, trihydroxystearin and Chemoderm® 1001/B fragrance. Chemoderm®is a registered trademark of Firmenich Inc.

    VUSION Ointment is a smooth, uniform, white ointment.

  • Drug Information Provided by National Library of Medicine (NLM).