Drug Information for PEPCID (Salix Pharmaceuticals, Inc): DESCRIPTION

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  • The active ingredient in PEPCID*Registered trademark of MERCK & CO., Inc., Whitehouse Station, NJ and is used under license.(famotidine) is a histamine H2‑receptor antagonist. Famotidine is N-(aminosulfonyl)-3-[[[2-[(diaminomethylene) amino]-4-thiazolyl]methyl]thio]propanimidamide. The empirical formula of famotidine is C8H15N7O2S3 and its molecular weight is 337.43. Its structural formula is:

    Famotidine is a white to pale yellow crystalline compound that is freely soluble in glacial acetic acid, slightly soluble in methanol, very slightly soluble in water, and practically insoluble in ethanol.

    Each 5 mL of the oral suspension when prepared as directed contains 40 mg of famotidine and the following inactive ingredients: citric acid, flavors, microcrystalline cellulose and carboxymethylcellulose sodium, sucrose and xanthan gum. Added as preservatives are sodium benzoate 0.1%, sodium methylparaben 0.1%, and sodium propylparaben 0.02%.

  • Drug Information Provided by National Library of Medicine (NLM).
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