Drug Information for Meloxicam Tablets USP 7.5 mg and 15 mg (Apotex Corp): DESCRIPTION

Meloxicam, an oxicam derivative, is a member of the enolic acid group of nonsteroidal anti-inflammatory drugs (NSAIDs). Each light yellow colored tablet contains meloxicam 7.5 mg and light yellow colored tablet contains meloxicam 15 mg for oral administration. It is chemically designated as 4-hydroxy-2-methyl-N-(5-methyl-2-thiazolyl)-2-H-1,2-benzothiazine-3-carboxamide-1,1-dioxide. The molecular weight is 351.4. Its empirical formula is C₁₄H₁₃N₃O₄S₂ and it has the following structural formula.

Meloxicam is a pastel yellow solid, practically insoluble in water, with higher solubility observed in strong acids and bases. It is very slightly soluble in methanol. Meloxicam has an apparent partition coefficient (log P)_app = 0.1 in n-octanol/buffer pH 7.4. Meloxicam has pKa values of 1.1 and 4.2.

Meloxicam is available as a tablet for oral administration containing 7.5 mg or 15 mg meloxicam.

The inactive ingredients in meloxicam tablets, USP include colloidal silicon dioxide, crospovidone, Iron oxide (Ferric Oxide) (in 15 mg tablets only) lactose monohydrate, magnesium stearate, microcrystalline cellulose, povidone and sodium citrate dihydrate.