Drug Information for CILOSTAZOL TABLETS (Apotex Corp.): CONTRAINDICATIONS

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  • Cilostazol and several of its metabolites are inhibitors of phosphodiesterase III. Several drugs with this pharmacologic effect have caused decreased survival compared to placebo in patients with class III-IV congestive heart failure. Cilostazol is contraindicated in patients with congestive heart failure of any severity.

    Cilostazol is contraindicated in patients with haemostatic disorders or active pathologic bleeding, such as bleeding peptic ulcer and intracranial bleeding. Cilostazol inhibits platelet aggregation in a reversible manner.

    Cilostazol is contraindicated in patients with known or suspected hypersensitivity to any of its components.

  • Drug Information Provided by National Library of Medicine (NLM).
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